Program Lock Pro
Lock and unlock any program on your pc, including IE, Outlook, AOL, AIM, and more. You can even lock your control panel with one button click. Other features include the ability to choose your own message to display if anyone attempts to run one of your locked programs, and also includes... Easy to use interface shows you current status of all locked programs, and allows you to easily click and unlock as you wish. ... Allows the entire PC to remain active and running, and it only locks and prevents access to the programs that you specify.
http://www.nettrials.com/program-lock-protect/locktr.exe - 608Kb - Download - Screenshot

Computer Lock Up
Computer Lock Up utility enables to lock computer access quickly as well as efficiently by means of password protection at the time the user is absent. At the moment when computer is locked up all hot keys and the mouse are switched off and the locking screen is showed. ... Also it's possible to lock up the computer at Windows startup or when the program is launched. ... The unique technology of key spy protection makes password capturing absolutely impossible at the time when the password is entered.
http://www.rixler.com/cgi-bin/download.pl?file=complock.zip - 616Kb - Download - Screenshot

Instant Lock
Easy, Fast and Secure Cutting Edge instant Lock technology has a perfect combination of speed and security. It locks GBs of data in a second! Once you lock your folders with instant Lock they will stay completely secure and invisible. Even when you boot from Safe Mode/Another Operating System or... Thanks to instant Lock, now you can enjoy using your computer, with a peace of mind. ... Unique Instant Lock technology came to life, after a long R&D period. ... It is powerful but it's also safe and foolproof.
http://www.softcns.com/downloads/softcns/iilockstp.exe - 72Kb - Download - Screenshot

Lock my Folder
Lock my Folder is a new folder password protected software which can help you lock your files, folders and disks with your personal password. Prevent people from viewing, editing, altering your folders as easy as 1-2-3. Locking files, folders, and drives is the best way to guarantee that nobody... You will be asked to type in a password when you open Lock ny Folder at the first time. ... If you do type a different password, Lock my Folder will prompt you for a correction. ... Lock files, folder and disk with secure encryption and password protection.
http://www.qksoft.com/lock-my-folder/lockmyfolder.exe - 1Mb - Download - Screenshot

Lock It Down
Lock It Down is a powerful software that locks content sensitive files and folders using advanced file encryption methods. It has options for secure mailing of encrypted files and exclusive viewing of locked files and folders. A password wallet and a file shredder are other available features.
http://lockitdown.com/lockitdown.exe - 2Mb - Download - Screenshot

Lock Folder
Lock Folder is a new security tool that lets you lock your files and folders with your personal password. Now nobody but you can access your most sensitive information. Locking folders and files also effectively protects you from malicious programs, such as viruses, worms and trojans. ... Here is how Lock Folder works - all you have to do is to drag file or folder you want to lock to Lock Folder window, and the rest is done automatically. ... Here is the important part - Lock Folder uses the encryption standards approved by the US Government.
http://www.realclicks.com/LockFolder/LockFolder.exe - 14Kb - Download - Screenshot

Lock It Down - Free Edition
Lock It Down Free Edition is a powerful software that locks content sensitive files and folders using advanced file encryption methods. It has options for secure mailing of encrypted files and exclusive viewing of locked files and folders. A password wallet and a file shredder are other...
http://free.lockitdown.com/freelockitdown.exe - 1Mb - Download - Screenshot

Lock Folder XP
Lock Folder XP is a new security tool that lets you lock your files, folders and drives with your personal password. Now nobody but you can access your most sensitive information. Locking folders, files and drives also effectively protects you from malicious programs, such as viruses, worms and... Here is how Lock Folder XP works - all you have to do is to drag file or folder you want to lock to Lock Folder XP window, and the rest is done automatically. ... But don't think that Lock Folder XP can only be used in the corporate environment - this application is perfect for home as well.
http://www.everstrike.com/download/lockfldr.exe - 1Mb - Download - Screenshot

PC Security
Lock down your system like never before. Exercize total control over your computer with the following security options: Explorer Control, File Lock, Folder Lock, System Lock, Internet Lock, Shortcut/Program Lock, Restricted System, Window Lock, intruder Detection with Alarm, Flexible and... A very powerful and easy to use protection utility.
http://www.tropsoft.com/pcsecurity.exe - 1Mb - Download - Screenshot

the Software Safe
Secret information, images, PIN-codes, passwords. Store them securely in this Safe on your PC. No more difficult codes to remember! With the personal locks, only YOU are able to open it. You can use a password, but with the personal locks, you don't need to remember difficult codes anymore! ... You may open files directly from the Safe Copy and paste or write text into 2 notebooks which may contain several pages with secret information The screen lock enables you to lock the screen with a password With the time lock, others will have serious trouble in trying to find the solution to your...
http://products.jaytown.com/SoftwareSafe/SoftwareSafe20e.exe - 6Mb - Download - Screenshot