RegexBuddy
RegexBuddy is your perfect companion for working with regular expressions. Easily create regular expressions that match exactly what you want. Clearly understand complex regexes written by others. Use plain English building blocks instead of or in addition to the standard regex syntax. ... Use the regex in your source code with code snippets automatically adjusted to the particulars of C#, Visual Basic, Java, C, C++, Delphi, Perl, PHP, Python, JavaScript, VBScript, Ruby, etc. ... Collect and document libraries of regular expressions for future reuse.
http://www.regexbuddy.com/cgi-bin/SetupRegexBuddyDemo.exe - 3Mb - Download - Screenshot

PatternHelper
Makes it easy for developers AND beginners to design and test patterns. Patterns written with perl regular expressions, egrep regex, MS Word or Brief pattern matching languages can be designed and tested with syntax highlighting and a slick test facility. ... Default patterns can also be chosen from a list. ... PatternHelper can run stand-alone, and also integrates with TextPipe Pro and a host of other applications.
http://www.datamystic.com/patternhelper.exe - 1Mb - Download - Screenshot

MeLite
MeLite (pronounced M ? E Lite), the latest programming tool from Multi Edit Software, Inc. provides exceptional power for a reduced rate. Geared towards the beginning programmer and student, MeLite gives you Intelligent Language Support with Smart Indenting, code templates, brace/construct... Regex Support? ... Once youre text is found, its highlighted throughout the entire file. ... Find text as you type incrementally. ... Define the perfect parameter with regular expression support. ... As with its bigger brother Multi-Edit, MeLite has one of the most configurable and fast search/replace...
http://www.multiedit.com/downloads/upgrade/SetupMeLite910.exe - 5Mb - Download - Screenshot